Scam Feels the Pinch

Scam Feels the Pinch

The paper by Movileanu et al. (2001) in this issue of The Journal describes a test of the applicability of the substituted-cysteine-accessibility method (SCAM; Akabas et al., 1992; Akabas et al., 1994) to the problem of locating the narrowest region of a channel lumen. Movileanu et al. (2001) use unusually large sulfhydryldirected reagents to probe the wide bore channel formed by Staphylococcal...

Big science feels the pinch in Europe.

The swine flu scam?

There is a conspiracy theory about nearly everything. So claims that swine flu was a scam come as no surprise. 'This was a pandemic that never really was' according to Paul Flynn, MP who prepared a recent report on the flu pandemic for the Council of Europe. 1 The report expresses alarm about the way the pandemic was handled. It criticizes the proportionality of the response and argues that ove...

Scam Light Field Rendering

In this thesis we present a new variant of the light field representation that supports improved image reconstruction by accommodating sparse correspondence information. This places our representation somewhere between a pure, two-plane parameterized, light field and a lumigraph representation, with its continuous geometric proxy. Our approach factors the rays of a light field into one of two s...

A chaperone feels the heat

JCB • VOLUME 167 • NUMBER 2 • 2004 190 A chaperone feels the heat chaperone is supposed to keep its cool when temperatures get hot. But Syed Rizvi, Laura Mancino, Malini Raghavan (University of Michigan, Ann Arbor, MI), and colleagues show that calreticulin—a glycoprotein chaperone—starts to melt in the heat. The resulting structural changes actually improve its chaperone activity and may also ...